Treatment of hayfever with loratadine a new non sedating antihistamine Hot women pose in chat rooms
First-generation OTC antihistamines include diphenhydramine (eg, Benadryl), chlorpheniramine (eg, Chlor-Trimeton), and clemastine (eg, Tavist); second-generation products include fexofenadine (eg, Allegra), loratadine (eg, Claritin and Alavert), and cetirizine (eg, Zyrtec).Because some second-generation antihistamines are less likely to cross the blood-brain barrier than first-generation antihistamines, they are associated with fewer nervous system effects, such as drowsiness.Both corticosteroid sprays and antihistamines can prevent allergy symptoms such as sneezing, runny nose, congestion and watery eyes when used continuously.But very few patients take these medications continuously.The effects of fexofenadine, diphenhydramine, alcohol, and placebo were assessed in a randomized, double-blind, 4-treatment, 4-period crossover trial of 40 licensed drivers with seasonal AR aged 25 to 44 years.Fexofenadine 60 mg, diphenhydramine 50 mg, alcohol (blood concentration approximately 0.1%), or placebo were administered at weekly intervals before participants drove 1 hour in the Iowa Driving Simulator.Similar results were observed in another study of fexofenadine and cetirizine with 821 patients.
Pregnant or breastfeeding women should consult a clinician prior to taking any of the 3 products, and all are contraindicated in renal dysfunction (physician consultation recommended).
Efficacy in AR Symptom Relief Results from clinical studies indicate that fexofenadine (Allegra) and cetirizine (Zyrtec) generally have a quicker onset of action in AR than loratadine (Claritin).
Those given fexofenadine demonstrated statistically equivalent improvement in allergy symptoms as those given cetirizine.
There are many effective treatments available for AR; however, patients may be confused by product labeling.
Pharmacists can inform and educate patients about available OTC products, point out differences in labeling, and help patients determine which medication is best for their needs.AR can be associated with comorbidities, such as asthma, sinusitis, otitis media, and sleep apnea.